In his pamphlet “The Doctrine of Original Sin” John Wesley argues that nearly all unhappiness can be traced to sin.
If you inquire into the troubles under which your neighbor, your acquaintance, or one you casually talk with, labours, still you will find the far greater part of them arise form some fault, either of the sufferer or of others; so that still sin is at the root of trouble, and it is unholiness which causes unhappiness.
Note, he is not strictly “blaming the victim” here. He imagines that the sins that lead to unhappiness are sometimes inflicted upon us rather than brought upon ourselves. Yet, it is still sin.
Many families are miserable through want. They have not the conveniences, if the necessaries, of life. Why have they not? Because they will not work: Were they diligent, they would want nothing. Or, if not idle, they are wasteful; they squander away, in short time, what might have served for many years. Others, indeed, are diligent and frugal too; but a treacherous friend, or a malicious enemy, has ruined them; or they groan under the hand of the oppressor; or the extortioner has entered into their labours. You see, then, in all these cases want (though in various ways) is the effect of sin.
And the effects persist because of sin.
But is there no rich man near? none that could relieve these innocent sufferers, without impairing his own fortune? Yes; but he thinks of nothing less. They may rot and perish for him. See, more sin is implied in their suffering.
The point of the tract is not social diagnosis, but it suggests to me a Christian way of talking about social problems. Whether it is lack of health care or poverty or drug abuse or sex trade or neglect and abuse or murder, the Christian question is not “what sociological or cultural factors were at play.” The Christian question is “where is sin at work in this situation?”
Finding an answer, the Christian works to destroy the work of the devil by removing sin through conviction, confession, conversion, forgiveness, baptism, eucharist, prayer, and the other means at the disposal of the people of God.
I am a part-time local pastor serving 
The doctrine of original sin is surely more humbling to man than the opposite: And I know not what honour we can pay to God, if we think man came out of His hands in the condition wherein he is now.
Excellent point, John. The-church-as-the-church has no particular sociological expertise that the world does not have. For the sake of love, Christians should want a good sociological (and psychological and economic and all the other sciences) analyses of the worlds problems, but these are areas of common grace or natural law. Individual Christians may be gifted in these areas, but that is not the same as seeing this work as the work of the-church-as-the-church. You’ve rightly identified the church’s unique role in addressing the world’s problems.